The Importance of PGT-M. How Preimplantation Genetic Testing Can Transform Family Planning

Some of you might already know about PGT-A, a process that checks embryos to make sure they have the right number of chromosomes before implantation. It helps lower the risks of miscarriages and genetic abnormalities-a crucial step for many.

But for some, that's not enough. They want extra reassurance, especially when it comes to inherited genetic conditions.

That's where PGT-M comes in. It adds another layer of protection, helping to screen for specific genetic disorders before pregnancy even begins. Let's break it down and see if it might be the right option for you.

What is PGT-M?

Imagine you and your partner are excited to start a family, but you recently discovered that one of you carries a genetic conditionmaybe it runs in your family, or perhaps you were unaware until now. You worry about passing it on to your child and what that might mean for their future. This is where PGT-M (Preimplantation Genetic Testing for Monogenic Disorders) comes in.

PGT-M is a special test done during IVF to check embryos for specific inherited genetic conditions before implantation. Simply put, it helps make sure only the healthiest embryos, free from the disorder, are chosen for pregnancy.

This gives you more control and peace of mind in your family planning journey, knowing youre giving your future baby the best possible start in life.

How Does PGT-M Work?

PGT-M is an additional step in the IVF process, a widely used fertility treatment where eggs and sperm are combined outside the body to create embryos (at Genea, this is done using ICSI-Intracytoplasmic Sperm Injection).

1. Ovarian Stimulation & Egg Retrieval - Medication is given to stimulate the ovaries, allowing multiple eggs to develop. These eggs are then carefully retrieved.
   
2. Fertilization - The retrieved eggs are fertilized with sperm in a laboratory, creating embryos.
   
3. Embryo Biopsy - A small sample of cells is taken from each embryo for genetic testing.
   
4. Genetic Analysis - The sampled cells are analyzed to detect specific genetic mutations.
   
5. Embryo Selection & Transfer - Only embryos that do not carry the identified genetic disorder are chosen for implantation, increasing the chances of a healthy pregnancy and baby.

Who is PGT-M for?

PGT-M is ideal for those who have concerns about passing on genetic conditions. It can be especially helpful if:

1. You or your partner are carriers of a genetic disorder - Even if you dont show symptoms, your child could inherit the condition.
   
2. Theres a family history of genetic diseases - If conditions like cystic fibrosis or thalassemia run in your family, PGT-M can help reduce the risk.
   
3. You've had a child with a genetic condition - If youve experienced this before, PGT-M helps prevent it from happening again.
   
4. You're already doing IVF and want extra reassurance - Since the embryos are already being created, adding PGT-M is a simple way to ensure the healthiest choice.
   

Benefits of PGT-M

PGT-M helps parents feel more at ease by reducing the risk of passing genetic diseases to their children. For many families, this means avoiding difficult decisions later in pregnancy. Instead of waiting for prenatal tests to confirm a disorder, PGT-M allows parents to act early, improving IVF success rates and offering reassurance that their child will have the best possible start in life. Its a proactive approach that helps prevent "monogenic disorders"

What are Monogenic Disorders?

Some genetic conditions are passed down through families due to a single gene mutation. These are known as monogenic disorders, and they can lead to lifelong health challenges. Some of the most common include:

• Cystic Fibrosis Affects lung function and digestion.
  
• Thalassemia A blood disorder requiring lifelong treatment. See the success stories of couples who are thalassemia carriers Click
  
• Duchenne Muscular Dystrophy Causes progressive muscle weakness.
  

At Genea Thailand, we are dedicated to advancing fertility treatments through cutting-edge technology and personalized care. Whether it's PGT-A for chromosome screening for abnormalities and gender or PGT-M for inherited genetic conditions, our goal is simple-giving every baby the healthiest possible start in life.

Located in Bangkok, our state-of-the-art facility offers seamless fertility solutions, guided by a team of world-class specialists. If you're ready to take the next step in your fertility journey, Genea Thailand is here to support you every step of the way.